CENTALE INCORPORATED (OTCBB: CTAL)
"Up 350.00% on Wednesday"

Detailed Quote: http://www.otcpicks.com/quotes/CTAL.php

Centale, Inc. engages in the design and distribution of desktop software applications in the United States. Its products primarily include the Catalyst EV, a desktop communications platform, which is programmable and interactive; ComPro that provides time sensitive information to the financial services industry; and the Community AlertPro, which offers emergency alerts to the university campus. The company was incorporated in 1998 as Safe Harbour Health Care Properties, Ltd. and changed its name to Centale, Inc. in 2004. The company is based in East Aurora, New York.

CTAL News:

April 2 - Centale, Inc. Acquires NexxNow China, Inc. Via Share Exchange Agreement

Centale, Inc. (OTCBB: CTAL) announced that it has acquired NexxNow China, Inc. via a share exchange agreement.

NexxNow China, Inc.'s primary business initiative is to become a premier exporter of sports related media content to China. Initially NexxNow will focus on the delivery of US Minor League Basketball and Street Ball content/culture to China via television, broadband and mobile distribution. NexxNow China, Inc. will remain a wholly owned subsidiary of Centale, Inc.

CTAL, the parent corporation, expects to announce a name change and the new Board of Directors in the coming weeks.

CTAL will operate as a diversified media company that focuses on media rights acquisition/ownership and distribution in addition to live event ownership/management and advertising/media sales.

In an effort to assure an orderly flow of information to the financial markets the company will announce all recent, present and future material information to include: media rights and inventory owned/acquired, corporate structure, new website, advisory board formation, key strategic alliances and merger/acquisition candidates.

Information on the company and a fact sheet can be found on www.nexxnow.com.

POW! ENTERTAINMENT (OTC: POWN)
"Up 116.67% on Wednesday"

Detailed Quote: http://www.otcpicks.com/quotes/POWN.php

POW! (Purveyors of Wonder) Entertainment Inc., an advanced media and entertainment company, was founded by world-famous comic book and motion picture icon Stan Lee, together with award-winning producer Gill Champion and intellectual property specialist Arthur Lieberman, Esq. POW!’s principals have extensive backgrounds in the entertainment industry encompassing the creation, production and licensing of original intellectual properties, including some of the most successful entertainment franchises of all time. POW!, capitalizing on this combined expertise, specializes in franchises for the entertainment industry, including animation and live-action feature films, plus television, DVDs, video games, merchandising and related ancillary markets, all of which contribute to global expansion. POW! partners with other individuals and entities of entertainment’s top echelon, including studios and networks, in the creation, licensing and distribution of new POW! character franchises.

POWN News:

March 6 - Comic Book Icon Stan Lee Takes Aim at Political Humor in New Book

With the release of "Election Daze," Lee returns to his humor roots

POW Entertainment, Inc. (OTC: POWN) announces a new book by Stan Lee. When superhero creator Stan Lee releases his new book of political humor, the expression “Super Tuesday” will take on a whole new meaning.

The name Stan Lee is usually synonymous with the famed Marvel Comics characters he co-created, such as Spider-Man, Iron Man, The Hulk, The Fantastic Four, The X-Men and many others.

Yet, many people don’t know that Lee has a soft spot for writing humor and he’s showcasing his gag-writing skills with the release of his new book, “Election Daze.” The book features his irrepressible, wildly funny dialogue balloons which accompany eye-catching photos by Capitol Hill photographer, Lauren Victoria Burke.

The subjects of the photos range from Hillary Clinton, Barack Obama, John McCain, and President Bush, to political celebrities such as George Clooney, Chuck Norris, and Stephen Colbert among others. “I’ve always gotten a kick out of combining far-out captions with serious pictures,” says Lee. “It’s a great change of pace from writing fantasy tales, although sometimes politics seems more like fantasy than my own stories.”

Stan Lee first published a book of photo humor back in 1961 called “Golfer’s Anonymous.” The golf-themed book utilized the same formula--humorous dialogue and captions, with photos of people on the links. Fans everywhere gobbled it up and it quickly sold out its entire run. Lee recalls that he was so busy writing his superhero stories at that time that he never got around to following it up with similar books.

However, at a recent comic book convention where Stan was making a guest appearance, a fan asked him to autograph an old, carefully preserved copy of “Golfers Anonymous.” Lee was happy to comply. “I had almost forgotten about that book. But, seeing it after all those years made me wonder if this wouldn’t be the perfect time to write a similar book, but this time zeroing in on the political campaign that’s on everyone’s lips.”

Stan mentioned his idea to publisher Tom Filsinger who enthusiastically agreed that this was the right time and the right market for such a book. “I loved the idea,” said Filsinger, aware that political personalities are particularly ripe for Lee’s offbeat type of humor.

“Election Daze” focuses on what politicians and celebrities “might have been saying” from the beginning of the presidential primaries and beyond. “Stan’s book will turn out to be a perfect keepsake for this historic election year,” said Filsinger.

The success of “Election Daze” will undoubtedly lead to the publication of an entire new series of Stan Lee’s books of photo humor. “They’ll deal with everything people are interested in — sports, music, movies, TV, and celebrities of every type. And that’s just for starters!” says an ebullient Lee.

So the man best known for superhero icons such as Spider-Man, now adds humor books to his amazing list of published works as he adds, with a smile, “After years of writing stories to keep readers on the edge of their seats, it’s fun to write a book that’ll make them kick back with laughter.”

“Election Daze,” which is available for pre-order on the Internet, is scheduled to arrive in bookstores like Barnes & Noble at the end of March. Stan Lee, ever the busy author and creator, is making several appearances that will coincide with the release of the book, including the New York Comic Con on April 18-20, Borders in Washington, D.C. on April 21, and BookExpo America in Los Angeles at the end of May.

MEDICAL INSTITUTIONAL SERVICES HOLDINGS (OTC: MIHS)
"Up 75.00% on Wednesday"

Detailed Quote: http://www.otcpicks.com/quotes/MIHS.php

MIHS is a wholesale distributor of medical supplies to physician's offices, clinical laboratories, urgent care centers and hospitals. MIHS utilizes numerous methods of marketing its products, including traditional office visits as well as a physician network system. All services and products are provided via the web. MIHS has one of the most extensive online ordering systems in the nation. MIHS also has a 24 hour delivery system which makes it the most proficient ordering system in health care today. MIHS also has a Minority Business Certification wherein the company can bid on major contracts with hospitals nationwide.

MIHS News:

April 1 - Medical Institutional Services Holdings Signs New President

Medical Institutional Services Holdings, Inc. (OTC: MIHS) announced that it has signed Mr. Ronald Berman as President of MIHS. Mr. Berman joins MIHS with over 30 years of sales and health related experience. Originally of Silver Springs, Maryland, he is a graduate of the University of Maryland with degrees in Business Administration and Accounting. "Ron Berman brings extensive experience in direct and Internet sales to MIHS. His years of success in business will add a tremendous dimension to the organization," said Ulysses Felder, MIHS V.P. and Director. Mr. Berman's first project will be to head the expansion of the organization into new arenas such as the exportation of medical supplies to Latin America — a massive growth market. MIHS will continue to grow with the finest team of executives available in health care.

NOTCH NOVELTY CORPORATION (OTC: NHNV)
"Up 56.25% on Wednesday"

Detailed Quote: http://www.otcpicks.com/quotes/PHGI.php

Notch Novelty Corporation engages in the manufacture and sale of novelty items. It sells sign goods to distributors and retailers in the dollar, drug, and grocery industries in the United States and Canada. The company, formerly known as M.A. Notch Corporation, was founded in 1958 and changed its name to Notch Novelty Corporation in 2005. Notch Novelty is based in Tucson, Arizona.

NHNV News:

April 1 - Notch Novelty Announces Merger and Reorganization

Notch Novelty Corporation (OTC: NHNV) announces that it has formally executed a merger/acquisition agreement and will be changing its primary business focus.

On Tuesday, March 25, 2008, the company entered into an agreement to acquire Atlantic Energy Solutions, a New York Corporation. Under this agreement, Notch Novelty will acquire 100% of Atlantic Energy in exchange for the issuance of 100 million newly issued and restricted shares. Management of Notch Novelty intends, in conjunction with the holders of the majority of shares of common stock, to change the Company name to reflect the current primary business. In addition, the current Chief Executive Officer, Brett Weiss, will be replaced by Tim Brock. Mr. Brock will serve as both Chief Executive Officer and Chairman of the Board. In conjunction with this merger, Mr. Weiss will purchase all present assets and liabilities of Notch Novelty Corp., in return for the delivery of 61,000,000 currently issued & outstanding shares currently held by Mr. Weiss.

Founded over 12 years ago, Atlantic is a green energy company that focuses on energy efficiency and conservation. Last year, Atlantic generated over 7.5 million dollars in revenue and has signed proposals totaling more than 45 million dollars in potential revenue for 2008 & 2009.

This merger reorganization agreement requires normal and customary state and federal filings. The Company will make every effort to fully update all disclosures in a timely manner with all appropriate agencies.

ABOUT ATLANTIC ENERGY SOLUTIONS, INC.

Atlantic Energy, founded in 1992, is a globally accredited Energy Services Company (ESCO) that identifies, implements and finances projects designed to improve the overall efficiency of energy usage.

Atlantic assesses the energy demands and usages of municipal, corporate and industrial complexes to improve conservation and apply measures to boaster savings at the consumer level. The company incorporates the latest technologies, including wind and solar energy generation. Our services focus on energy and financial strategies to achieve comprehensive, innovative and cost-beneficial improvements.

The company is currently headquartered in Saratoga Springs, NY. Atlantic also has offices in Manhattan NY, Fulton NY and Fairfield NJ.

For more information, please visit us at http://atlanticenergy.net.

ENZYME ENVIRONMENTAL (OTC: EESO)
"Up 33.33% on Wednesday"

Detailed Quote: http://www.otcpicks.com/quotes/EESO.php

Enzyme Consultants Organization (ECO) is a U.S. based manufacturer of industrial and agricultural enzyme products. All manufacturing, testing, and formulating are conducted in its manufacturing plant, located in Fort Wayne, Indiana. ECO strives to become a leader in ecological friendly or “Green Products” targeting the industrial and agricultural markets. It is our goal to have the best performing products on the market in each industry. Developing a growing and satisfied customer base is our number one marketing strategy.

EESO News:

April 2 - Enzyme Environmental Solutions Clarifies Rumors

Enzyme Environmental Solutions Inc. (OTC: EESO) CEO Jared Hochstedler announced that the company has entered into negotiations to purchase up to 25% of the common stock of Enzyme Solutions Inc. ("another Fort Wayne, Indiana based enzyme company").

Hochstedler commented, "EESO is negotiating with private shareholders of ESI to purchase up to 25% of ESI common stock. I was one of the original founders of ESI and believe it would be a natural fit for EESO and ESI to have a closer relationship. I further would like to make clear that these negotiations will only include terms that would be non dilutive to the current EESO shareholders."

Hochstedler further commented, "We were informed on April 1, 2008 that there was a caveat emptor status placed on the pinksheets.com website for our company's trading symbol. We contacted Pinksheets.com and were in formed that their standard practice is that whenever a company goes through a name change without filing new information the status goes to caveat emptor. We requested an opportunity to file the appropriate information immediately, however the request was denied and that the status will remain on Pinksheets.com for a minimum of their standard 30 days. I want all shareholders to be assured that we will assemble and file the requested disclosure packet just as soon as possible and without delay. This was a shock to have this done with no advance warning and I would like to encourage any shareholder that has questions regarding the status change to call pinksheets.com at (212) 896-4420. Rest assured that our goal is to build shareholder value."

The company would also like to confirm that as of April 2, 2008 the outstanding share count remains at 223,716,398 commons shares issued and outstanding.

COMMONWEALTH BIOTECHNOLOGIES (NASD: CBTE)
"Up 30.96% on Wednesday"

Detailed Quote: http://www.otcpicks.com/quotes/CBTE.php

Commonwealth Biotechnologies, Inc. provides life sciences research and development outsourcing services. It offers various solutions to the biotechnology industry, as well as to the academic institutions, government agencies, and pharmaceutical companies worldwide. The company provides an array of synthetic and analytical technologies in the areas of bio-defense, laboratory support, and contract research. Commonwealth Biotechnologies provides genetic identity testing, including paternity, forensic, and convicted offender DNA index system analyses. In addition, it offers peptide libraries and research grade peptides, and peptide therapeutics custom peptide synthesis. The company operates various specialty labs, including Biosafety level 3 labs for bacteriology and virology, a DNA reference Lab, calorimetry and mass spectrometry labs, cell culture and fermentation labs, high throughput DNA sequence labs, and peptide synthesis labs. Commonwealth Biotechnologies was founded in 1992 and is based in Richmond, Virginia.

CBTE News:

April 2 - Exelgen Ltd., a Subsidiary of Commonwealth Biotechnologies, Inc., Announces Two New Major Drug Discovery Collaborations

One Deal Could Potentially Generate in Excess of $25 Million in Research, Milestone and Royalty Payments

Exelgen, Ltd., a wholly owned subsidiary of Commonwealth Biotechnologies, Inc. (NASD: CBTE) (CBI) and a leading provider of drug discovery chemistry services and small molecule products, announced today that it has entered into two new drug discovery collaborations: one with a leading US pharmaceutical company and one with a major European pharmaceutical company. Given the proprietary nature of the collaborations both partners declined to be named.

"With our new European partner, we have entered into a broad-based collaboration to discover and develop novel small-molecule therapeutics for use in the fields of CNS; Alzheimer's disease, neuro-inflammation and type-2 diabetes," said Mark Warne, Managing Director at Exelgen. "Under the terms of the agreement, based on compounds discovered by Exelgen, our partner will receive an option to license the compounds and collaborate in specific programs. With the signing of the agreement, our partner will make an initial up-front cash payment to Exelgen for exclusivity on certain program assets and have the option to continue development of the assets in collaboration with Exelgen.” If this collaboration proves successful and a drug candidate is identified, Exelgen would receive ongoing support through additional research funding and, more importantly, will be eligible to receive success-based milestones of up to $25 million and additional royalties on any product sales.

Speaking about the collaboration with the leading US pharmaceutical company, Mark Hober, Vice President of Business Development and Marketing for CBI, indicated that, "This collaboration draws on Exelgen's proven track record in computational design and library synthesis and is expected to generate revenues of up to $900,000 over the coming months. This contract follows on the heels of several other successful projects with this client."

Paul D'Sylva, CEO of CBI summarized these two wins by saying "These collaborations capitalize on Exelgen's drug discovery capabilities and underscores the value of our drug discovery platform and therapeutic area expertise. We are delighted to join forces with these two partners to discover novel drug candidates that will help to address unmet medical needs."

ABOUT EXELGEN LIMITED

Exelgen Ltd, formerly Tripos Discovery Research Ltd, is a leading knowledge driven, drug discovery services business that provides pharmaceutical and biotechnology companies with novel approaches to drug discovery. Applying proprietary computational design and therapeutic medicinal chemistry tools and expertise, Exelgen is able to reduce drug discovery timelines by up to 30%. Since 1997, Exelgen has been offering compound libraries under the LeadQuest® brand, screening libraries under the LeadScreen® brand and custom de novo compound libraries under the LeadSelect® brand. Further information about Exelgen and its capabilities for high quality compound library production can be found at www.exelgen.com.