OTCPicks.com

For Thursday, November 13th

GCHK, BSTI, NXPC, PGOG, RNNM
ANVH, PSPM, ISTA, TOBC, GFRE, NIHK

Our Stocks to Watch today include GreenChek Technology Inc. (OTCBB: GCHK), Brite-Strike Tactical Illumination Products Inc. (OTC: BSTI), NeXplore Corp. (OTC: NXPC), Perf Go Green Holdings Inc. (OTCBB: PGOG), Ronn Motor Co. (OTC: RNNM), The Anviron Holding Co. (OTC: ANVH), PureSpectrum Inc. (OTC: PSPM), ISTA Pharmaceuticals Inc. (Nasdaq: ISTA), Tower Bancorp Inc. (OTCBB: TOBC), Gulf Resources Inc. (OTCBB: GFRE) and Nighthawk Systems Inc. (OTCBB: NIHK).

FEATURED COMPANY

QMCI

GREENCHEK TECHNOLOGY INCORPORATED (OTCBB: GCHK)
"Up 3.08% in morning trading"

Detailed Quote: http://www.otcpicks.com/quotes/GCHK.php

Company Profile:
http://www.otcpicks.com/greenchek-technology/greenchek-technology.htm

GreenChek Technology, Inc. manufactures and distributes hydrogen injection technology devices that primarily focus on mobile transportation applications and industrial generative power applications. It also provides mobile greenhouse gas emissions reduction technology. The company's Onboard Hydrogen Generation and Injection technology is used for emissions reduction technology and fuel economy enhancement in trucks, locomotives, and automobile engines. It has operations in the United States, Canada, Asia, and Europe. The company, formerly known as Ridgestone Resources, Inc., was founded in 2006 and is headquartered in San Francisco, California.

GCHK News:

November 13 - GreenChek Signs Strategic European Distribution Agreement

GreenChek Technology Inc. (OTCBB: GCHK), a leading globally focused provider of hydrogen based technology for mobile transportation and stationary power generation applications, reported today that they have signed a strategic European distribution agreement with Technical Environmental Solutions Europe Ltd. (TESEL). TESEL is a world-class and world-renowned distribution Company focused in Europe. The November 4, 2008, announcement of the Letter of Intent has been finalized by both parties.

GreenChek manufactures an emission reducing device simply known as the ERD 1.0, which can be retrofitted to any vehicle or combustible engine regardless of fuel source. This device reduces vehicle emissions as well as increases fuel economy.

GreenChek’s Chief Strategy Officer, Donald Walling, stated, “We are very pleased to have signed this agreement with TESEL. Our proven ERD addresses the specific needs of multiple verticals in the European transportation industry. The agreement with TESEL marks a major milestone on route to our plan for aggressive global distribution of the ERD unit.” Walling added, “Our partnership with TESEL gives us the knowledge and ability to address and navigate complex European Government and intricate European transportation industry needs.”


FEATURED COMPANY

IMAGE

BRITE-STRIKE TECHNOLOGIES INCORPORATED (OTC: BSTI)

Detailed Quote: www.otcpicks.com/quotes/BSTI.php

Company Profile: http://www.otcpicks.com/brite-strike/brite-strike.htm

Brite-Strike Tactical Illumination Products, Inc. was started by two police officers to create world-class tactical LED flashlights that had the features that police officers and citizens need to keep them safe. Brite-Strike makes a promise to always use the latest technology, world-class components, highest design and manufacturing standards, so consumers can rely on Brite-Strike products when they are needed.

BSTI News:

November 6 - Brite-Strike Tactical Illumination Products, Inc.'s Personal Protection System to Be Featured in the Prestigious Frontgate Christmas Catalog

Brite-Strike Tactical Illumination Products, Inc. (OTC: BSTI) announced that its "Lightning Strike" Personal Protection System will be featured in Frontgate's national Christmas catalog, and that shipments for the initial order will begin this week. The product is also being carried at 28 BJ's Wholesale Club locations, which can be found at www.brite-strike.com.

"This product, for the money, may be the most effective defensive tool available for women today, particularly in preventing assaults and rapes," said Glenn Bushee, President of Brite-Strike. "The gift set includes a powerful, but compact, tactical flashlight, with the patented tactical touch hi-low-strobe switch, a leather holster, as well as a personal safety alarm, that can emit a shrieking noise of up to 125 db, and can be effective in warding off dogs and assailants. The package includes other accessories, and is packaged in a presentation gift box."

The company also announced that sales of its flagship model, the "Tactical Blue-Dot" flashlight, currently being featured in the Herrington Catalog, remain very strong, and are expected to significantly exceed last year's sales, even in this challenging economic environment. The company has been informed that its product is the top selling product in the catalog at that price-point. "In tough economic times, such as now, the number of robberies and assaults rise dramatically, which increases the demand for all our products," said Mr. Bushee, president of Brite-Strike.

In other news, the company announced that it had shipped its first order to the Pennsylvania Prison System, an area where the company see's significant growth opportunities. The company is also currently in discussions with one major national retailer for the placement of the "Lightning Strike," and is in late-stage testing with one branch of the US Military.

The company recently filed a Form 15 with the SEC. This form is in preparation for the company's financial audit, and intent to file as an SEC reporting company, with application to file for listing on the OTC BB the first half of 2009.

"We are extremely optimistic about the future of Brite-Strike. We feel the current share price dramatically undervalues the company, and its long-term growth prospects. We project dramatic increase in revenues over the next several years, both from our existing product line, as well as new products," said Mr. Bushee. "We appreciate our loyal shareholders, and in acknowledgement of their support, we would like to offer any shareholders ordering product through customer service, at 781-585-5509, a discount on all their purchases, with free gift-wrapping for all our customers for the holiday season."


FEATURED COMPANY

QMCI

NEXPLORE CORPORATION (OTC: NXPC)

Detailed Quote: www.otcpicks.com/quotes/NXPC.php

Company Profile: www.otcpicks.com/nexplore/nexplore.htm

NeXplore Technologies is developing a Web 2.0 search engine and an assortment of social networking portals and tools that will enable users to personalize their Web experience and tailor it to their unique needs, interests, and online pursuits. The Company’s social computing platform, MyCircle.com, offers an enhanced, user-friendly graphical interface search engine, combined with innovative backend technology, which enables users to improve the way they connect with information and other people on the Worldwide Web. MyCircle’s Web 2.0 interface provides users with an online tool for sharing their Blogs, Voice-Over IP, photos and documents, podcasts and videocasts, classified advertising, instant messages, SMS text messages, Chat and personal profiles.

NXPC News:

November 11 - Former Microsoft VP Rowland Hanson Joins NeXplore Advisory Board

Branding Mastermind Behind Microsoft Windows to Guide Business Development and Growth Strategy for NeXplore Search

NeXplore Corporation (OTC: NXPC) announced the appointment of Rowland Hanson to the NeXplore Corporation board of advisors.

Currently CEO of business strategy consulting firm The HMC Company, Mr. Hanson will draw upon his vast experience building brands and growing market share for some of the world's best known, high-growth companies to guide business development and growth initiatives for NeXplore Search (www.NeXplore.com), an innovative Web 2.0 search engine optimized for a superior end-user experience, rich-media display and social network integration.

Prior to founding The HMC Company, Mr. Hanson served as vice president of corporate communications for Microsoft, where he developed and executed the company's highly acclaimed branding strategy which included the market introduction of Microsoft's most popular product -- a graphical interface that Mr. Hanson named "Windows."

"What excites me about NeXplore Search is that the visually rich user interface engages consumers and, at the same time, reinvigorates an advertising medium that, although proven, is losing its luster as text overload leaves more and more consumers with search fatigue," said Hanson. "NeXplore Search is well-positioned to be at the forefront of the next generation of search, and I am pleased to be involved with NeXplore at such a pivotal moment. I look forward to helping the NeXplore executive team take this product and company to the next level."

"Rowland Hanson brings immense business experience, marketing insight and branding wisdom to NeXplore," said Edward Mandel, CEO of NeXplore Corporation. "His proven track record maps out perfectly with NeXplore's aggressive growth goals. Rowland's guidance will be instrumental as we move forward with strategic initiatives to accelerate popularity of NeXplore Search among consumers and drive traction of NeXplore Search among leading brand and direct-response advertisers. We are thrilled to have a professional of Rowland's caliber and distinction serving on the NeXplore advisory board."

Prior to Microsoft, Mr. Hanson served as vice president of worldwide marketing for Neutrogena Corporation, a skin care and cosmetics company that registered phenomenal growth through new product introductions and global partnering before being acquired by Johnson & Johnson.

Over the last several years, Mr. Hanson served as a consultant, CEO, president, and board of director member for several emerging companies.

Mr. Hanson served as president, CEO, and chairman of Amaze Inc., a multi-media software publisher of popular products such as The Far Side, Trivial Pursuit, Bloom County, and Berlitz theme computer calendars and screen savers. Hanson negotiated the sale of Amaze to Delrina Corporation.

Mr. Hanson was founder, CEO, and Chairman of iTravel Corporation, an exclusive developer of multi-media travel guides for United Airlines, United Vacations, and the travel agency network. Hanson negotiated the successful sale of iTravel to StarPress.

Mr. Hanson was business development consultant, branding consultant, and board member of ColdHeat, a company whose proprietary material science led to the successful introduction of several new consumer small appliances.

Mr. Hanson served as a business development consultant, branding consultant, and board member of The Nautilus Group, the developer and marketer of well-known fitness brands such as Bowflex, Nautilus, Schwinn Fitness, and StairMaster.

Mr. Hanson founded The b EQUAL Company with a mission to strengthen the child/parent bond by creating games that make learning a fun, interactive, family event. The b EQUAL Company partners included A&E (The History Channel / Biography), National Geographic, and DreamWorks, Discovery, among others. Hanson negotiated the merging of The b EQUAL Company into Specialty Board Games (SBG) of Toronto, Canada.

Mr. Hanson holds a BBA from Loyola University and an MBA from the Wharton School of Business (University of Pennsylvania).


FEATURED COMPANY

QMCI

PERF GO GREEN HOLDINGS INCORPORATED (OTCBB: PGOG)

Detailed Quote: www.otcpicks.com/quotes/PGOG.php

Company Profile:
http://www.otcpicks.com/perf-go-green/perf-go-green.htm

Perf Go Green Holdings, Inc. is engaged in the creation and global marketing of 100% eco-friendly, non-toxic, food-contact-compliant, biodegradable plastic products. All Perf Go Green products are made from recycled plastics and completely break down in landfill within two years, leaving no toxic or visible residue, as compared to other plastics that take hundreds of years. Perf Go Green’s corporate name reflects its “Go Green” mission to develop, market and distribute biodegradable plastic products as a practical and viable solution to eliminating plastic waste from the world environment.

PGOG News:

November 11 - Perf Go Green Expands Business Development Team

Partners With GEM Business Development to Broaden Retail and Consumer Awareness and Accelerate Go-to-Market Approach

Perf Go Green Holdings, Inc. (OTCBB: PGOG) (“Perf Go Green”), a marketer and distributor of biodegradable plastics, announced the expansion of its business development team through a partnership with GEM Business Development. GEM will assist Perf Go Green in building brand equity with consumers, gaining additional retail distribution and leveraging its partnerships with strategic retailers.

The GEM team will be led by Rebecca Gournay, President, who has more than 15 years of consumer packaged goods experience in Sales Management & Marketing. Prior to co-founding GEM, she served as Franchise Business Director, Marketing & Sales Operations at Johnson & Johnson. While at Johnson & Johnson, she worked on leading brands such as Splenda®, Lactaid®, Band-Aid®, Tylenol® and Aveeno®.

“GEM's deep knowledge of the consumer packaged goods industry will be a great asset to Perf Go Green as we continue to grow,” said Chief Marketing Officer Linda Daniels. “We picked GEM to help us refine our go-to-market strategy in the retail marketplace, enabling shoppers to make better environmental choices when they purchase household products. Our expanded team of seasoned executives will deliver a comprehensive consumer marketing plan, refine our go-to-market structure, and support retailers in their sustainability efforts by focusing on our authentic brand to drive category sales.”

Founded in November 2007, Perf Go Green premiered at the March 2008 International Home and Housewares Show in Chicago, where its products were honored for their design quality and innovation. Perf Go Green is now shipping seven prominent biodegradable plastic products categories, including 13-gallon kitchen trash bags, 30- and 39-gallon lawn & leaf bags, plastic drop cloths, Doggie Duty Bags™ and cat pan liners. Its products are available nationwide at more than 12,000 retail outlets. They are also sold online through Amazon.com and drugstore.com.


FEATURED COMPANY

QMCI

RONN MOTOR COMPANY (OTC: RNNM)

Detailed Quote: http://www.otcpicks.com/quotes/RNNM.php

Company Profile: http://www.otcpicks.com/ronn-motor-company.htm

Headquartered in Austin, Texas, Ronn Motor Company, Inc. is a design and manufacturing company focused on the leading edge engineering of environmentally friendly, finely built premium automobiles and technology. These technology systems include Hydrogen Fuel, Fuel cells, and Plug in-electrics will be incorporated into our automobiles and made available for aftermarket applications. Our products, coupled with RMC's core values of a strong sense of ethics, environmental sensitivity and premium quality, position the company as one of the new leaders in an automotive industry transitioning toward fuel efficiency.

RNNM News:

November 11 - Ronn Motor Company: 'Speculative Buy' Rating, Target Price $0.84 by Beacon Equity Research

Ronn Motor Company (OTC: RNNM) has received a Speculative Buy rating with a price target of $0.84 by Beacon Analyst, Victor Sula, Ph.D.

The full report is available at www.beaconequity.com/main/Page-data/Adpages/RNNM.

In the report, the analyst writes, “The Company’s H2GOTM system offers an immediate solution to the transportation industry for greenhouse gases emissions reduction. With the long term high oil prices environment a reality, RNNM solution has the potential to rapidly gather market share and report double-to-triple digits growth in sales. … Over the long term, the Company plans to maintain a double-digit growth in revenue due to increased acceptance of its offering and rollout of Hydrogen/Electric Plug-in Hybrid in 2010.”

Comparable companies in the hydrogen or exotic car manufacturing segment include Ballard Power Systems Inc. (Nasdaq: BLDP), FuelCell Energy Inc. (Nasdaq: FCEL), Plug Power Inc. (Nasdaq: PLUG) and Ener1 Inc. (AMEX: HEV).

November 10 - Frigette's Projection of Three-Year Retail Sales of One Million Units of Ronn Motor Company's H2GO™ Real Time Hydrogen Injection System Reinforced After Strong SEMA Response

Ronn Motor Company, Inc. (OTC: RNNM) announced that after strong SEMA response, the Company is reinforcing Frigette's projection of three-year retail sales of Ronn Motor Company's proprietary H2GO(TM) Real-Time Hydrogen Injection system could be potentially one million units globally, producing retail revenues potentially of up to $1 Billion in retail sales globally within the three years.

Ronn Maxwell, CEO of Ronn Motor Company, said, "The H2GO(TM) Real-Time Hydrogen Injection system was recently unveiled by Tommy DuPont, Publisher of the world renowned 'DuPont Registry' and revealed to the world at SEMA, the world's largest and most recognized automotive aftermarket convention show. The H2GO(TM) system is the catalyst behind the world's First Eco-Exotic sports car named the 'SCORPION(TM).' The Scorpion(TM) and the H2GO(TM) system were one of the most talked about features at this year's show and received unprecedented media coverage for its one-of-a-kind Green technologies that increase fuel mileage between 15-35% on any internal combustion engine while reducing noxious emissions to nearly zero.

"We are currently finalizing Global Distribution and manufacturing contracts with Frigette which is the largest aftermarket automotive manufacturer and distributor in the U.S. with nine regional distribution centers and over 5,000 distributors. Frigette products are sold directly or indirectly to over 170,000 locations worldwide. Frigette has distribution presence in the U.S.A., Europe, China, India and Russia."

Ronn Motor Company projections are based on assumptions from Frigette directly. In a prior news release, Mr. Phillip Kreymer, Director of Marketing at Frigette, said sales of one million units over the next three years are easily within Frigette's manufacturing and distribution capabilities and with a suggested retail price of $999.00 that would possibly produce revenues in the one billion dollar range.

Frigette is supplying products to many Original Equipment vehicle manufacturers including General Motors, Ford, Honda, Isuzu, Jaguar, Mazda, Nissan, and Subaru, and has been awarded the coveted "Q1 Supplier Award" by Ford Motor Company and the "First Team Supplier Award" by Nissan Motors of America. We also supply products to thirty-nine (39) OEM Recreational Vehicle manufacturers.

Frigette quality control standards have been approved by Chrysler Motors, Ford Motor Company, General Motors, Honda, Hyundai, Isuzu, Jaguar, Mazda, Nissan, Saturn, Subaru, GAZ, VAZ, Volvo, Winnebago, and others. Frigette's distributor network and key installers number in excess of 500 and have installation capabilities to support the Frigette products to the new car dealers who do not wish to perform installations. This assures the O.E.M. manufacturer that quality products, which they have approved, can be installed on their vehicles even though the car dealer may not wish to make the installation.


STOCKS TO WATCH

THE ANVIRON HOLDING COMPANY (OTC: ANVH)
"Up 64.71% in morning trading"

Detailed Quote: http://www.otcpicks.com/quotes/ANVH.php

Anviron is a company dedicated to bringing to market "Clean Solutions to Complex Problems" by offering a wide range of biodegradable, environmentally friendly products and technologies that will substitute for many of the hazardous chemicals commonly used all over the world. For information about Anviron and its product offerings visit www.anviron.com.

ANVH News:

November 13 - Anviron Reports October Financial Results up 157% over Budget

The Anviron Holding Company (OTC: ANVH) (“Anviron”), a manufacturer and marketer of "Clean & Green" products and technology, announced financial results for the month ending October 31, 2008 were posted on www.pinksheets.com. The Company continues to post record revenue with October posting more than $1.65M and year to date numbers posting of $17.1 million and net profit of $6.75 million, or $0.06 per basic share.

Highlights:

* Record 1st Quarter Revenue of $12.6 million, up 20.1% from budget.
* October 2008 Revenue of $1.65M, up 157% from budget.
* Fourth consecutive quarter of positive operational growth and profits.
* Laboratory JV anticipated generating $15 million in annual sales for fiscal 2009.
* Signing of four new contracts for NuSoil sales for FYE 2009.
* NuSoil selected as technology of choice for reclamation of closed Mine operation.
* DustControl and RoadBinder lead product sales in Fiscal-Year 2009.

“Anviron continues to deliver outstanding results, posting our fourth consecutive quarter of profitability as well as positive operating cash flow. Revenue increased 157% over budget for the fiscal year 2009, reflecting the ongoing demand for our organic products,” said Anviron COO Steve Young.

“Our expanding profits continue to attract attention in the public market, as demonstrated by continued coverage on the Emerging Issuer’s website, www.emergingissuer.com. As we grow, the staff, board and management will continue to focus on our expanding business,” said Marcie Corbin, CFO of Anviron. StockVest.com has just completed the presentation of Anviron at this year's Washington DC Money Show, November 6-8. For 30 years now, The Money Show has spearheaded the field of investment trade shows attracting tens of thousands and remains #1 in the nation today.


PURESPECTRUM INCORPORATED (OTC: PSPM)
"Up 23.08% in morning trading"

Detailed Quote: http://www.otcpicks.com/quotes/PSPM.php

PureSpectrum is a publicly traded technology company founded and headquartered in Savannah, Ga. The company's values are grounded in an awareness of the increasing urgency to identify more efficient energy solutions. PureSpectrum currently holds the rights to multiple patents and patent applications related to an electronic ballast design which would produce a soft switching environment during power conversion for artificial lighting. PureSpectrum will continue its commitment to researching, developing and refining ideas that will provide the most energy efficient, cost effective methods for powering artificial light. For more information on PureSpectrum, call (912) 961-4980 or visit www.purespectrumlighting.com.

PSPM News:

November 13 - PureSpectrum, Inc. Enters Into Agreement With Emirates International Capital Advisory

Equity Investment and Advisory Contract Expected to Close Within 60 Days

PureSpectrum, Inc. (OTC: PSPM) has entered into an agreement with Emirates International Capital Advisory which provides a minimum equity investment of $5 million in PureSpectrum.

Following the completion of due diligence and other formalities, PureSpectrum expects the investment transaction to close within the next 60 days.

Emirates International Capital Advisory (EICA) is a leading financial advisory and management firm with investments in real estate, technology, minerals and global equity markets on three continents. The company's core investment areas are the Middle East, North Africa and Latin America, and EICA is actively involved in trading, investing and researching in the global equity, debt, currency and commodity markets.

"Pure Spectrum's business model and product are an exact fit to EICA's business direction. We believe that the global crises being witnessed today will finally be lead out by investments in the clean power and in the reduction and excessive use of pollutants. Today with governments taking a more active role in promoting efficient businesses we see a huge upside in businesses developing breakthrough and useable technologies such as Pure Spectrum," said Mr. Arash Masom Senior Managing Director of Emirates International Capital Advisory.

"PureSpectrum is fortunate to be able to partner with EICA, a well established firm in the Middle East and throughout the world," said PureSpectrum president and CEO Lee Vanatta. "We are looking forward to collaborating with EICA to identify future business opportunities for PureSpectrum in Dubai and the other United Arab Emirates."

During the past year, PureSpectrum has positioned itself on the leading edge of technology development to enhance the performance of energy efficient lighting products and is poised to make a significant contribution to the multibillion dollar global lighting industry. The company's innovative and cost-effective electronic ballast circuitry for dimmable Compact Fluorescent Light (CFL) bulbs and linear fluorescent light bulbs enables unprecedented performance and will allow dimmable energy efficient lighting products to be sold at a lower cost than commercially available dimmable products.

PureSpectrum is currently negotiating to finalize a contract manufacturing agreement for its consumer friendly CFL bulbs and expects to be able to distribute proprietary dimmable CFLs in North American Free Trade Association (NAFTA) countries in the first quarter of 2009. All PureSpectrum products will be compliant with established performance standards set forth by Energy Star, Underwriters Laboratory (UL) and the Federal Communications Commission (FCC).


ISTA PHARMACEUTICALS INCORPORATED (NASDAQ: ISTA)
"Up 37.50% in morning trading"

Detailed Quote: http://www.otcpicks.com/quotes/ISTA.php

ISTA Pharmaceuticals is an ophthalmic pharmaceutical company. ISTA's products and product candidates addressing the $4.7 billion U.S. prescription ophthalmic industry include therapies for inflammation, ocular pain, glaucoma, allergy, and dry eye. The Company currently markets three products and is developing a strong product pipeline to fuel future growth and market share. The Company's product development and commercialization strategy is to launch a new product every 12 to 18 months, thereby continuing its growth to become the leading niche ophthalmic pharmaceutical company in the U.S.

ISTA News:

October 30 - ISTA Pharmaceuticals Reports Third Quarter 2008 Financial Results

ISTA Pharmaceuticals, Inc. (Nasdaq: ISTA), an ophthalmic pharmaceutical company, reported financial results for the third quarter ended September 30, 2008. ISTA reported net revenue for the three months ended September 30, 2008, of $21.7 million, a 36% increase over net revenue for the three months ended September 30, 2007. On a quarter-over-quarter basis, net revenue increased 22% over the second quarter of 2008.

"Our growth has moved ISTA up to the fifth largest branded ophthalmic pharmaceutical company position, surpassing Bausch & Lomb. Xibrom and Istalol are leading the way as the two fastest-growing ophthalmic products in the US, both outpacing the growth of their markets," stated Vicente Anido, Jr., Ph.D., President and Chief Executive Officer of ISTA Pharmaceuticals. "During the third quarter, three of our longest-term shareholders provided us with a $65 million credit facility. This financing allowed us to repay our convertible debt, and it gives us the flexibility to continue to grow our business."

"We are making solid progress with our R&D pipeline. This quarter, we expect to report preliminary results from our Xibrom once-daily Phase III studies and, assuming positive results, we expect to file the supplemental NDA in early 2009. We are planning to file the Bepreve NDA before the end of this year. Assuming acceptance and timely review by the FDA, we anticipate receiving approval to market Bepreve in the second half of 2009. With regard to ecabet sodium, our candidate for the treatment of dry eye, we plan to report preliminary Phase II results this quarter. These results will provide the clinical validation we need before making the decision to initiate Phase III trials with ecabet sodium.

"Finally, we are noticing that the FDA is taking longer to review new study protocols and the number of cataract surgeries this fall is lower than anticipated, which may be linked to the economic slow down. We believe that both of these dynamics are lengthening the enrollment times in our studies. As such, we now expect results from our T-Pred studies in early 2009. With three late-stage products, we believe the upcoming months will be an exciting time for us."

Third Quarter Operating Details

Gross margin for the third quarter ended September 30, 2008 was 73%, or $15.9 million, as compared to 74%, or $11.7 million, for the same period in 2007. The change in gross margin as a percentage of revenue is due primarily to an increase in the royalty rate for Xibrom and other costs such as wholesaler distribution agreements. Inventories held by wholesale customers at September 30, 2008 remained relatively unchanged from June 30, 2008.

Research and development expenses were $7.8 million and $8.4 million in the third quarters of 2008 and 2007, respectively. The research and development expenses for the third quarter ended September 30, 2007 included $3.0 million in milestone expenses, of which $2.0 million was associated with an upfront payment paid to Mitsubishi Tanabe for the licensing of the nasal dosage form of bepotastine. The increase in research and development expenses for the third quarter of 2008, excluding the prior year quarter's milestone expenses of $3.0 million, was primarily the result of an increase in clinical development costs, which include clinical investigator fees, study monitoring costs and data management costs, due to the work performed on our key product candidates: Xibrom 0.09% once daily, Bepreve Phase III efficacy, Bepreve safety and T-Pred studies. Research and development expenses during the third quarter of 2008 included $0.2 million in stock-based compensation expense.

Selling, general, and administrative expenses for the third quarter ended September 30, 2008 were $13.2 million, as compared to $11.0 million for the same period in 2007. The $2.2 million increase in selling, general and administrative expenses in 2008 as compared to 2007 primarily results from higher sales and marketing expenses associated with the expansion of our sales force, which occurred in the first quarter of 2008 ($0.6 million), an overall increase in administrative costs, primarily related to legal expenses ($1.3 million) and an increase in our stock-based compensation expense ($0.3 million). Selling, general, and administrative expenses during the third quarter of 2008 include $0.8 million in stock-based compensation expense.

Interest expense for the third quarter ended September 30, 2008 was $2.4 million, as compared to $1.2 million for the same period in 2007. The increase of $1.2 million is primarily attributable to the write off of the unamortized deferred financing costs, the unamortized debt discount and the value of the embedded derivative associated with the senior subordinated convertible notes, which were paid in full as of the quarter ended September 30, 2008.

The net loss for the third quarter of 2008 was $7.4 million, or $0.22 per share, compared with a net loss of $8.2 million, or $0.25 per share, for the same period in 2007. At September 30, 2008, ISTA had cash and cash equivalents of $22.1 million, plus $4.3 million in long-term investments in auction rate securities.

Third Quarter 2008 and Subsequent Financing Information

ISTA entered into an agreement with long-term shareholders, Deerfield Management, Sprout Group and Sanderling Ventures to provide ISTA with up to $65 million in financing through a flexible credit facility at 6.5% interest.

ISTA drew $40 million from the September 2008 facility at closing, issued 12.5 million warrants at $1.41 and subsequently repaid its convertible notes due 2011 for par, or $40 million, plus accrued interest.

During October 2008, ISTA drew the remaining $25 million from the September 2008 credit facility and issued 2.5 million warrants at $1.41. ISTA made this draw in October to strengthen its cash position during this time of uncertainty in the credit and other financial markets.

2008 Financial Outlook

We continue to expect our full-year 2008 net revenue will be approximately $75 to $82 million.

We continue to expect our full-year 2008 gross margin will be approximately 70% to 73%, subject to change based on revenue mix.

Depending upon the progress of our clinical and pre-clinical programs, we continue to expect that our research and development expenses for the full year of 2008 will be approximately $34 to $38 million, including stock-based compensation expense, which we continue to estimate will be approximately $0.5 to $1 million.

We anticipate that our selling, general, and administrative expenses for the full-year 2008 will be approximately $50 to $54 million, including stock-based compensation expense, which we continue to estimate will be approximately $3.5 to $4.5 million. We have been tracking to the high end of our SG&A guidance due to increased legal expenses.

We anticipate that our 2008 interest expense will be approximately $6 to $7 million. Included in those costs is $3.5 to $4 million of interest expense on our debt agreements and $2.5 to $3 million of non-cash amortization costs related to our embedded derivative and debt discount on both our old convertible notes and our new credit facility.

We expect to end 2008 with a cash balance of $25 to $35 million, depending upon fluctuations in working capital.


TOWER BANCORP INCORPORATED (OTCBB: TOBC)
"Up 31.58% in morning trading"

Detailed Quote: http://www.otcpicks.com/quotes/TOBC.php

Tower Bancorp, Inc. operates as the holding company for The First National Bank of Greencastle, which provides commercial banking and bank related services primarily in south central Pennsylvania. It accepts demand, time, and savings deposits. The company's loan portfolio comprises agribusiness, commercial, residential, consumer, and business loans. The company serves individuals, corporations, partnerships, associations, municipalities, and other governmental bodies. As of December 31, 2007, it operated sixteen branches located in Quincy, Shady Grove, Waynesboro, Mercersburg, Chambersburg, Laurich, Rozerville, McConnellsburg, Needmore, and Fort Loudon, Pennsylvania; and Hancock and Hagerstown, Maryland. The company was founded in 1864 and is based in Greencastle, Pennsylvania.

TOBC News:

November 13 - Tower Bancorp, Inc. and Its Subsidiary, The First National Bank of Greencastle, Forms Partnership with Graystone Bank

CEOs Define Proactive, Revenue-Driven Strategy

Jeffrey B. Shank, president and CEO of Tower Bancorp, Inc. (OTCBB: TOBC), the holding company of The First National Bank of Greencastle, and Andrew Samuel, chairman and CEO of Graystone Financial Corp., the holding company of Graystone Bank, announced the execution of a definitive agreement to form a partnership of their financial institutions whose combined assets will exceed $1.2 billion with offices headquartered in Harrisburg, Pennsylvania. Samuel and Shank affirmed that the alliance is a proactive, revenue-driven strategy, not a cost-saving response to the current financial climate.

Both community-based institutions will continue operating under their established brands and their respective customers will receive the same high-level of services and products from the familiar faces at their existing locations. The only visible transition will be the operation of current First National Bank of Greencastle branches as “Tower Bank, a division of Graystone Tower Bank” and the operation of current Graystone Bank branches as “Graystone Bank, a division of Graystone Tower Bank.”

As part of the transaction, Tower will exchange .42 share of Tower common stock for each outstanding share of Graystone Financial Corp. common stock. In addition, Tower will assume 199,750 outstanding stock options of Graystone to acquire shares of Graystone common stock. The transaction is structured to qualify as a “tax-free reorganization” and tax-free exchange of shares of common stock by the Graystone shareholders for shares of Tower common stock under the Internal Revenue Code. In addition, the definitive agreement provides that the Tower shareholders will receive a special cash dividend of $1.12 per share of Tower common stock prior to the effective date of the reorganization.

The definitive agreement also provides that the holding company shall remain Tower Bancorp, Inc. with 20 members of the Board of Directors, ten each designated by Tower and Graystone, respectively. The agreement also provides that Kermit G. Hicks shall continue to serve as Chairman of the Board of Tower Bancorp, Inc.

The significantly increased asset size and expanded employee base of more than 300 will enable the combined banks to provide even more personalized service to their customers. “We follow great people, and we have found an employee culture that matches our values. We are focused on a community bank model of honesty and integrity” said Samuel, founder of Graystone Bank in 2005.

“In early conversations, we discovered that our core company values are nearly identical and our commitment to strong local roots and relationships in the community are also identical. To find a sister institution with the same ideology is rare and compels us to capitalize on our strengths by combining efficiencies and increasing talent,” said Shank, whose 144-year-old bank has experienced steady growth in Fulton and Franklin counties and Washington County, Md.

“This partnership is a win-win for our employees, customers, shareholders, and the community,” said Samuel, who brings 25 years of banking experience to his three-year-old de novo institution. Graystone currently has 9 branches serving Centre, Cumberland, Dauphin, Lancaster, Lebanon, and York counties.

“The legacy of good banking stewardship and community and employee investment that Jeff has delivered under his leadership at First National Bank of Greencastle is what unites our institutions,” said Samuel. Jeff Shank has 35 years of banking knowledge.

Pending satisfaction of customary conditions and shareholder and regulatory approvals, the reorganization will take effect in early 2009. The new organizational structure, which will not affect products or services to customers, will operate under the holding company of Tower Bancorp, Inc. The allied institutions’ leadership team will include the following: Andrew Samuel, president and CEO of Tower Bancorp, Inc.; Jeffrey Renninger, EVP, COO of Tower Bancorp, Inc.; Jeffrey Shank, EVP of Tower Bancorp, Inc., president and CEO of Tower Bank, a division of Graystone Tower Bank; Janak Amin, EVP of Tower Bancorp, Inc., president and CEO of Graystone Bank, a division of Graystone Tower Bank; and Mark Merrill, EVP, CFO of Tower Bancorp, Inc.

“Our officers are held to a high community standard as are First National Bank of Greencastle’s. Our independence and motivation to return skills and resources to the community is not a policy, it’s a daily practice,” said Samuel.

Despite the credit conditions, both institutions have produced steady and progressive quarters of financial performance and growth, and combined will be a dominant institution in central Pennsylvania and northern Maryland. Although the stark contrast in founding dates separates the institutions, both Shank and Samuel believe this partnership is not a next-year transaction.

“Our alliance will set the stage for decades to come for community banking in our region. It accelerates our growth plan and sends a proactive, positive message to our customers and our competition: our roots run deep, our people are the finest, our customers are well-served,” said Samuel.

According to the Pennsylvania Department of Banking, there have been 11 bank mergers under their jurisdiction to date in 2008. Uncharacteristic of typical bank combinations, there are no scheduled branch closings and no branch overlaps in this relationship. After an initial evaluation period, both presidents concede that some duplicating positions may require streamlining.

“The union of the fastest growing and most successful de novo bank in Pennsylvania with the oldest independent bank in a three-county area cements the future of economic sustainability on our Main Street,” said Shank. “We’re excited to provide our communities with the increased financial opportunities that this alliance affords.”

The First National Bank of Greencastle is the sole subsidiary of Tower Bancorp, Inc., established in 1983 as a one-bank, publicly traded holding company to provide the communities it serves with local banking decision-making. Founded in 1864, FNBG is headquartered in Greencastle, Pennsylvania, and has 16 office locations in three counties. It is the oldest independent bank in the region. As of September 30, 2008, Tower Bancorp, Inc. had total assets of approximately $549.9 million, total net loans of $402.8 million, total deposits of $417.7 million, shareholders’ equity of $73.3 million, book value of $31.68 per share, and tangible book value of $23.80 per share. For the nine months ended September 30, 2008, Tower Bancorp, Inc. recognized net income of approximately $4.0 million.

Graystone Bank, operating under Graystone Financial Corp., was founded in 2005 and is headquartered in Harrisburg, Pennsylvania, with nine branches serving six counties. Recognized in 2006 as the #2 Best Places to Work in Pennsylvania and in 2007 as the #1 Best Places to Work in Pennsylvania, Graystone’s unparalleled competitive advantage is its 140 employees. At Graystone, a strong corporate culture and a clear vision has provided customers with uncompromising services and individualized solutions to every financial need. As of September 30, 2008, Graystone Financial Corp. had total assets of approximately $615.6 million, total net loans of $537.6 million, total deposits of $490.2 million, shareholders’ equity of $53.9 million, and book value and tangible book value of $8.29 per share. For the nine months ended September 30, 2008, Graystone Financial Corp. recognized net income of approximately $1.5 million.


GULF RESOURCES INCORPORATED (OTCBB: GFRE)
"Up 17.59% in morning trading"

Detailed Quote: http://www.otcpicks.com/quotes/GFRE.php

Gulf Resources, Inc., through its subsidiaries, manufactures and trades in bromine and crude salt in the People's Republic of China. Its bromine compounds are used for industry and agriculture applications, as well to form intermediates in organic synthesis. The bromine is used in brominated flame retardants, fumigants, water purification compounds, dyes, medicines, and disinfectants. The company also manufactures and sells chemical products used in oil and gas field exploration, oil and gas distribution, oil field drilling, wastewater processing, papermaking chemical agents, and inorganic chemicals. These chemical products include hydroxyl guar gum, demulsified agent, corrosion inhibitor for acidizing, bactericide, chelant, iron ion stabilizer, clay stabilizing agent, flocculants agent, remaining agent, and expanding agent with enhanced gentleness. In addition, it engages in the research and development of commonly used chemical products, as well as medicine intermediates. The company is based in Shouguang City, the People's Republic of China.

GFRE News:

November 13 - Gulf Resources to Present at Rodman & Renshaw Annual Global Investment Conference

Reaffirms full year 2008 revenue and net income guidance of $84-$90 million and $20-$23 million, respectively

Gulf Resources, Inc. (OTCBB: GFRE) (“Gulf Resources” or the “Company”), a leading manufacturer of bromine, crude salt and specialty chemical products in China, announced its financial results for the three and nine months ended September 30, 2008.

Third Quarter Highlights:

* Net revenue was $17.6 million, a year-over-year increase of 6.9%
* Gross profit was $6.2 million, a year-over-year decrease of 10.1%
* Net income was $3.7 million, or $0.04 per fully diluted share, down slightly from $3.9 million, or $0.04 per fully diluted share a year ago
* Cash totaled $22.9 million as of September 30, 2008
* Initiated an environmentally friendly additive production line
* Received $23 million in placed orders for the fourth quarter of 2008

Third Quarter 2008 Results

“During the third quarter, we experienced an expected slowdown in sales due to government imposed restrictions on production and distribution at many chemical factories in Beijing and Qingdao because of the Beijing 2008 Olympic Games held in August. However, we are happy to report that we have recently seen a significant recovery in purchase orders, particularly for bromine products and additives for oil and gas exploration and our capacity utilization has returned to pre-Olympic levels,” said Ming Yang, Chief Executive Officer of Gulf Resources. “We are still confident in our full year’s performance as we continue to see robust demand for bromine and chemical products, especially for environmentally friendly chemical compounds in China. Our rapidly expanded production capacity and increased production efficiency will further support our full year outlook.”

Gulf Resources’ net revenue in the third quarter of 2008 was $17.6 million, an increase of 6.9% from $16.4 million in the third quarter of 2007. The increase in net revenue was primarily attributable to the increased sales of the bromine and crude salt segment as a result of three bromine producing facilities acquired and integrated during the fourth quarter of 2007 and in the beginning of 2008.

Sales within the bromine and crude salt segment were $13.1 million, or 74.7% of the Company’s net revenue in the third quarter of 2008, a 20.5% increase from sales of $10.9 million or 66.2% of the Company’s net revenue in the third quarter of 2007 due to increased bromine production capacity. Sales in the chemical products segment were $4.5 million in the third quarter of 2008, compared to sales of $5.5 million in the third quarter of 2007. The restrictions on chemical manufacturers and transportation in the Beijing and Qingdao areas before and during the Olympic Games impacted sales of both bromine and chemical products during the quarter.

Gross profit in the third quarter of 2008 totaled $6.2 million, compared to $6.9 million in the third quarter of 2007 and gross profit margin was 35.1%, compared to 41.8% in the third quarter of 2007. The decrease in gross profit margin was due to increases in raw material and energy prices in China during the third quarter of 2008.

Operating expenses in the third quarter of 2008 were $1.1 million, compared to $0.7 million in the third quarter of 2007. Operating expenses were driven by increases in general and administrative expenses due to higher land tax fees and mineral resources compensation fees.

Income from operations in the third quarter of 2008 was $5.1 million, compared to $6.2 million in the third quarter of 2007. Operating margin was 29.0% in the third quarter of 2008, compared to 37.7% in the third quarter of 2007.

Income taxes were $1.4 million, a 37.6% decrease from $2.2 million in the third quarter of 2007. The Company’s effective tax rate was 26.8% compared to 35.8% in the year ago period due to reductions in the Chinese corporate income tax rates, which became effective January 1, 2008.

Net income was $3.7 million in the third quarter of 2008, a 5.3% decrease from $3.9 million in the third quarter of 2007. Basic and diluted earnings per share in third quarter of 2008 were $0.04, maintaining the level of the third quarter of 2007.

Nine Month Financial Results

Revenues for the first nine months of 2008 were $63.4 million, up 63.0% from $38.9 million in the first nine months of 2007. Gross profit was $25.3 million, up 58.0% from $16.0 million for the nine months of 2007. Gross margin was 39.9%, compared with 41.2% for the first nine months of 2007. Operating income was $22.1 million, up 49.1% from $14.8 million for the first nine months of fiscal 2007. Net income was $16.2 million, or $0.16 per basic and fully diluted share, an increase of 68.4% from $9.6 million, or $0.10 per basic and fully diluted share, for the same period a year ago.

Financial Condition

As of September 30, 2008, Gulf Resources had cash of $22.9 million, current liabilities of $17.5 million, long term debt of $18.3 million, and shareholders’ equity $45.7 million. At quarter end, working capital was $16.7 million and current ratio 1.95. During the nine months ended September 30, 2008, the Company generated $17.6 million in cash flow from operations, primarily attributable to net income. For the same period, the Company’s cash flow from investing activities totaled $17.4 million, mainly due to the addition of a new chemical production line and to the acquisition of additional mineral rights, property, plant and equipment to increase its bromine manufacturing capacity.

Recent Developments

In September 2008, Gulf Resources started production at a newly completed chemical production line particularly focusing on environmentally friendly additive products, such as solid lubricants and polyether lubricants, for use in oil and gas exploration. The line has an expected annual production capacity of 5,000 tons.

In September 2008, the Company also signed a three-month purchase agreement with Kuerle City Xingdong Trading Co., Ltd., a distributor of additive materials for oilfields in Xinjiang province, to deliver 800 tons of the recently developed oil and gas exploration additive products worth a total of $1.6 million. The Company expects to complete these orders by the end of fiscal 2008.

In October 2008, the Company announced that it has received approximately $23 million in customer orders for the fourth quarter of 2008. As a result, capacity utilization has recovered to levels achieved in the beginning of the year.

Business Outlook

Gulf Resources expects to continue expanding its bromine segment through both acquisitions and increased operating efficiencies. The Company is also looking at expanding its specialty chemicals production capacity to commercialize its recently developed pharmaceutical intermediate products.

The Company expects to increase profitability by the end of fiscal year 2008 as pressure from high raw material prices is likely to ease, due to the slowdown of the Chinese and global economy. Since mid-September 2008, raw material prices have decreased by an average of 30%, and gross margin is expected to recover to above 40% as a result.

“Long term demand for bromine is expected to remain strong in China even in a cooling economy, as the outlook for many of the downstream industries utilizing bromine, such as oil and gas exploration, continues to be promising. Raw material costs have demonstrated a decrease in October, which will likely boost our gross margin in the fourth quarter. We are also expecting to widen our industry exposure by expanding our chemical business into pharmaceutical intermediates in the near future,” concluded Mr. Ming Yang. “In terms of developing our business further through potential acquisitions and organic growth, our strong cash position will provide an advantage in today’s volatile market conditions.”

Gulf Resources reaffirms revenue and net income guidance for its fiscal year 2008 financial results, with expected revenue between $84 million to $90 million expected net income between $20 million to $23 million, and expected diluted earnings per share between $0.20 and $0.23. This guidance does not include the impact of any unusual charges.

Conference Call

Gulf Resources’ management will host a conference call at 10:00 a.m. ET on Friday, November 14, 2008 to discuss its results for the period ended September 30, 2008. To participate in this live conference call, please dial 888-419-5570 five to ten minutes prior to the scheduled conference call time. International callers should call 617-896-9871. The conference pass code is 114 091 16.

A replay of the conference call will be available for 14 days starting from 12:00 a.m. ET on Friday, November 14. To access the replay, call 888-286-8010. International callers should call 617-801-6888. The conference pass code is 446 528 39.


NIGHTHAWK SYSTEMS INCORPORATED (OTCBB: NIHK)
"Up 11.90% in morning trading"

Detailed Quote: http://www.otcpicks.com/quotes/NIHK.php

Nighthawk is a leading provider of intelligent devices and systems that allow for the centralized, on-demand management of assets and processes. Nighthawk products are used throughout the United States in a variety of mission critical applications, including remotely turning on/off and rebooting devices, activating alarms, and emergency notification, including the display of custom messages. Nighthawk’s IPTV set top boxes are utilized by the hospitality industry to provide in-room standard and high definition television and video on demand.

NIHK News:

November 12 - Nighthawk Systems Signs Agreement with Itron

Nighthawk Systems, Inc. (OTCBB: NIHK) (“Nighthawk”), a leading provider of wireless and IP-based control devices and solutions, announced that it has signed an agreement with Itron, Inc. (Nasdaq: ITRI) under which Nighthawk has granted Itron a nonexclusive right to promote, market and sell Nighthawk wireless power control products to its utility customers.

Nighthawk’s wireless, whole house disconnect technology will complement Itron’s proven automated meter reading (AMR) data collection suite, ChoiceConnect™, providing electric utilities with two-way communications capability to their customer’s meter. The utility will be able to connect, disconnect, or limit power to customers based on meter readings without rolling a truck and sending field personnel to the customer’s location. Nighthawk’s one-way CEO700 and two-way CEO800 series of disconnect units will enable the Itron team to tailor the best solution for their customers. Nighthawk’s collar-based solutions fit directly behind the Itron-equipped meter allowing for virtually seamless integration of a remote disconnect solution for either existing or new customers.

Itron provides a uniquely comprehensive portfolio of products and services to utilities in over 130 countries. Itron is the market share leader in the North American AMR market, deploying both drive-by and fixed network meter reading technology that allows meter reading to be performed without actually viewing or touching the meter with any other equipment.

H. Douglas Saathoff, Nighthawk’s CEO, commented, “I’m very happy to announce that we’ve entered into this agreement with Itron, which formally associates Nighthawk with perhaps the most well-known and well-respected provider of metering equipment in the world today. This agreement will allow Itron to incorporate Nighthawk’s technology into their own product offerings, and opens up the Itron sales and distribution network to Nighthawk. This is a significant step in the evolution of Nighthawk.”

“Itron certainly recognizes the potential value of combining Nighthawk’s growing wireless control capabilities with our ChoiceConnect suite,” said Philip Mezey, senior vice president and COO of Itron North America. “By building strategic partnerships with providers such as Nighthawk, we continue to enhance our innovative solutions, further helping utilities to better manage demand for an energized future.”

ABOUT ITRON

Itron is a leading technology provider and critical source of knowledge to the global energy and water industries. Itron operates in two divisions: as Itron in North America and as Actaris outside of North America. Our company is the world’s leading provider of metering, data collection and software solutions, with nearly 8,000 utilities worldwide relying on our technology to optimize the delivery and use of energy and water. Itron delivers industry leading solutions for electricity, gas and water utilities by offering meters; data collection and communication systems, including automated meter reading (AMR) and advanced metering infrastructure (AMI); meter data management and utility software applications; as well as comprehensive project management, installation and consulting services.

 
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